The pitching matchup looked to favor the Quakes on Tuesday in the second game of a three-game series with the 66ers.

Quakes starter Jeremy Thorne entered the game with a 4-7 record and a 4.60 ERA, but the Sixers were reduced to a “bullpen” game with left-hander Miguel Sanfler making his first start of the season.

Sanfler could only go two innings, but the rest of the staff filled in admirably and the Sixers defeated the Quakes 6-3 before an announced crowd of 2,214 at the Epicenter Tuesday.

The win improved the Sixers to 55-73 overall, 23-35 in the second half, just one game behind the Quakes (56-72, 26-32). Lancaster (53-75, 27-31) remained three games back of the Quakes.

Sanfler was picked up by David Pfeiffer, Jake McCarter (3-3), Eric Krebs, Brian Akin (although he didn’t retire any of the 2 batters he faced) and Marcel Prado (6th save), who combined to allow only two hits in the final seven innings.

The Quakes had only four hits, but drew 10 walks and left a season-high 14 runners on base (previous high was 12).

Meanwhile, the Sixers cracked 15 hits, including massive solo home runs by Andres Perez (to center, breaking a 3-3 tie in the sixth) and Alex Garabedian (in the eighth).

Perez drove in three runs, while Justin Fuller was 3-for-5 with a run and an RBI in his new leadoff spot for the Sixers.

The Sixers, who had lost seven in a row entering the week, have won the first two of the three-game series. The Quakes have lost a season-high six straight games.